Polyamines and apoptosis

Transmethylation, Polyamines and Apoptosis in Amyotrophic Lateral Sclerosis

Polyamines, PP2A and apoptosis M5:03041 R2 PROTEIN PHOSPHATASE 2A (PP2A) REGULATES APOPTOSIS IN IEC-6 CELLS

PROTEIN PHOSPHATASE 2A (PP2A) REGULATES APOPTOSIS IN IEC-6 CELLS Ramesh M. Ray, Sujoy Bhattacharya and Leonard R. Johnson Department of Physiology, University of Tennessee Health Science Center Memphis, Tennessee, 38163 Running title: Polyamines, PP2A and apoptosis Address correspondence to: Dr. Ramesh M. Ray, Department of Physiology, University of Tennessee Health Science Center, 894 Union Av...

Polyamines and prostatic cancer.

The importance of polyamines in prostatic growth and differentiation has prompted studies to evaluate the clinical relevance of the ornithine decarboxylase/polyamine system in prostatic cancer. These studies show that differences in biological behaviour of prostatic (cancer) cells are associated with changes in polyamine levels and/or the activity of their metabolic enzymes. Faulty antizyme reg...

Polyamines and plant alkaloids.

Naturally occurring alkaloids are nitrogenous compounds that constitute the pharmacogenically active basic principles of flowering plants. Alkaloids are classified into several biogenically related groups. Tobacco alkaloids are metabolised from polyamines and diamines putrescine and cadaverine. N-methyl transferase is the first enzyme in alkaloid biosynthetic pathway which drives the flow of ni...

Influence of estrogen and polyamines on mifepristone-induced apoptosis in prostate cancer cells.

PURPOSE Although androgens are the main steroids controlling the growth of prostate glands, estrogens are also important in the regulation of its growth. Prostate cancer cells, like other cancer cells, maintain high levels of polyamines. In LNCaP cells, apoptosis is induced by mifepristone. During the process of cell death, the regulation of ROS production, caspase-3 activation and poly (ADP-ri...